Lipoprotein metabolism Essay Example | Topics and Well Written Essays - 500 words

Lipoprotein metabolism - Essay Example This part accounts for the largest part of the cholesterol that is quantified as HDL-C in clinical laboratory. ÃŽ ±-HDLÂ  can be fractionated further by density into HDL3 and HDL2, by apolipoprotein composition and size. About 5-15% of apo A-1 in the human plasma is linked to pre–Î ²-electrophoretic mobility particles. This is further differentiated into pre–Î ²3-LpA-I, ÃŽ ²1-LpA-I and pre–Î ²2-LpA-I particles. These particles where reverse cholesterol transport occurs. This occurs in extravascular compartments. It is not clear where the HDL particles and pre–Î ²-electrophoretic mobility originates from. There are several mechanisms that have been proposed including cholesteryl ester transfer protein (CETP), direct interaction between cell membrane and free apolipoproteins, hepatic lipase (HL), release during the HDL interconversion by phospholipid transfer protein (PLTP) and direct secretion from enterocytes into plasma. High-density lipoprotein is produced in the intestine and liver. It plays a key role in the reverse cholesterol transport. By accepting free cholesterol from the peripheral tissues, HDL lowers the blood cholesterol levels. HDL exchanges lipids and proteins with other lipoproteins. It donates apoproteins E and C11 to nascent VLDL’s. HDL also produces a paraoxonase enzyme. This enzyme inhibits the oxidation of low-density lipoprotein. The HDL precursor particles can also absorb free cholesterol from the cell membrane in a process mediated by apoA-1, ApoA-IV and ATP binding cassette transporter 1. ApoA-1 is the HDL’s major apolipoprotein. It activates the cholesterol acyltransferase (LCAT) (a lecithin enzyme) that esterifies the free accepted cholesterol to increase the efficiency of cholesterol packaging for transport. By acquisition of additional esters, triglycerides, and apolipoproteins, the particles of HDL3 are transformed into HDL2 particles which are relatively la rger. By estension, HDL plays a role in transferring the

Irish Folk Costume Essay Example | Topics and Well Written Essays - 3250 words

Irish Folk Costume - Essay Example The revival of Irish dancing caused viewing of the Irish national dress as a colorful and flashy. However in ancient Ireland people traditionally wore leine (Irish for shirt), trews (Irish for trousers) and long brats (Irish for cloaks) fastened with a brooch. These pieces of clothes (leine and brat) were the basic elements of ancient Irish dress for people in the upper classes. These lasted from the earliest recorded times down to the 16th century. Irish national dresses worn by people back in the eighth century have had great influence on the dresses that Irish dancers wear today. If anyone wants to get an idea of how Irish peasants looked like in the eighth century, one should just have a look at the dresses worn today by Irish dances. The dresses used in their shows are updated replicas of traditional dresses decorated with elaborate Celtic designs from the Book of Kells and emphasized with a Tara Brooch which is pinned to the shawl. The traditional colorful costume of Irish peasants stayed actual up to the beginning of the 20 th century. The Gaelic League was created in 1893. The aim of this organization was to promote Irish nationalism. To reach this aim the League organized Irish dance classes and competitions called Feisanna, which is â€Å"Festival† in Irish. The purpose of these classes and competitions was to make sure that people were dancing the national dance. The organizers believed that if people danced national Irish dances they would not go in for any other dances that weren’t Irish, English dances specifically.